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On May 1, 2018, Seton Family of Hospitals broke ground on a 40,000-square-foot medical campus which is expected to open in 2019. The investment in this “neighborhood hospital” is estimated at $30 million and will include an emergency room, imaging services, 12 treatments rooms, inpatient beds, and medical office space. As part of a Performance Agreement with Seton Family of Hospitals, the EDC has agreed to construct an extension of Agnes Street from SH 304 to the eastern property line of the Bastrop Grove subdivision.

The St. David's Emergency Center in Bastrop is a full-service freestanding emergency department that does not have attached inpatient facilities. This Emergency Center serves as an extension of the St. David’s South Austin Medical Center. St. David’s Emergency Center operates 24 hours a day, seven days a week. It features 10 multi-purpose exam rooms, including a trauma room, and is staffed by board-certified emergency medicine physicians as well as trauma-certified nurses.

Seton Smithville Regional Hospital, located 13 miles east of Bastrop on Highway 71, is an acute care facility providing inpatient and outpatient services to Bastrop, Lee, Fayette and surrounding counties. Seton Smithville offers a comprehensive scope of services typically available only in large, urban hospitals. It is the mission of Seton Smithville Regional Hospital to promote the highest quality personalized healthcare, to be a strong community presence and to be the source for progressive diagnostic technology for the community. 

Lone Star Circle of Care, a federally qualified, multi-service community health center in Bastrop. It is a nonprofit organization serving the primary and behavioral health care needs of all individuals regardless of insurance status or ability to pay. Lone Star Circle of Care operates over 25 clinics throughout Central Texas.

The Lost Pines Center for Cancer Care is focused on providing cutting edge cancer treatment in a comfortable setting. Until recently, the treatment they provide required a lengthy drive to San Antonio or Austin. The physicians and staff at the Cancer Center are committed to creating a treatment environment that is more comfortable than the typical medical office. They provide a wide variety of support services and believe that education is an important part of their partnership with their patients.

The Lakeside Professional Building houses a variety of physicians, specialists, and medical related businesses, such as dermatology, cardiology, MRI and x-rays, and a medical laboratory.